Authorized by the Italian Ministry of Health for housing of transgenic and immunodeficient mice under specific pathogen-free conditions (SPF). It is composed of 9 independent rooms that host mice (360 Individually Ventilated Cages (IVC) per room) and 4 fully equipped laboratories. Animal health care is provided by the Animal Welfare Manager and by the veterinarian specialized in laboratory animals. The animal house is equipped with IVIS Spectrum (bioluminescence, fluorescence, 3D images), RS 2000 Small Animal and Cell Irradiator, X-RAD SmART Small Animal Image Guided Irradiator and dedicated micro-PET scanner (GE Healthcare eXplore VISTA).