Gastrointestinal Oncology
Milano
Via Giacomo Venezian, 1 , 20133 Milano MI
The Gastrointestinal Oncology Unit specializes in the diagnosis and medical treatment of tumors affecting the stomach and esophagus, small intestine, colon-rectum and anus, pancreas, biliary tract, appendix (including the clinical syndrome pseudomyxoma peritonei), as well as abdominal, thoracic, and cutaneous neuroendocrine tumors (including Merkel cell carcinoma).
Given their complexity, gastrointestinal tract neoplasms in our institution are managed through a diagnostic and therapeutic approach shared among multiple specialists from the very first patient visit. In collaboration with surgeons, gastroenterology endoscopists, radiologists, nutritionists, radiation therapists, palliative care physicians, and pathologists, a multidisciplinary treatment plan is developed. This multidisciplinary treatment plan ensures optimal timing and coordination of interventions and diagnostic procedures. Additionally, our Unit emphasizes the importance of patient comprehension of the disease and adjusts care, where feasible, to address individual needs, with careful consideration of communication and psychological factors. We are also engaged in research focused on minimizing potential disparities in access to care.
Each patient receives a cutting-edge care plan, and clinical research often allows us to offer innovative treatments such as those targeting genetic characteristics, immunotherapy, or novel treatment mechanisms.
Our team is deeply committed to designing and conducting academic clinical studies to improve practice and therapeutic strategies for gastrointestinal tumors. Some of our staff members hold significant positions in professional associations and scientific networks, such as the GONO Foundation, known for developing treatments recommended in international guidelines.
Our research has contributed to defining current treatment standards for gastrointestinal cancers, including colorectal and gastroesophageal carcinomas.
Finally, we actively participate in drafting national and international guidelines for the treatment of gastrointestinal tumors, serving as a global reference for clinical and scientific activities. Our team meets regularly to ensure synergy among different professionals (physicians, research nurses, study coordinators), maintain continuous scientific updates, and uphold consistency in therapeutic strategy formulation.
First SSN examinations can be booked through the same channels as other specialist services:
- switchboard INT: (+39) 02.2390 1.
- in person (CUP AMBULATORY GENERAL)
To have access to the first examination you need a ‘First oncological examination’ referral, issued by your general practitioner or other specialist, stating the diagnosis or suspected diagnosis.
Visits conducted through the National Health System necessarily require the presence of the patient
- Colorectal carcinoma
- Carcinomas of the stomach, gastroesophageal junction and oesophagus
- Carcinoma of the pancreas
- Carcinoma of the biliary tract
- Neuroendocrine tumours
- Mail: filippo.pietrantonio@istitutotumori.mi.it
- Mail: renata.spallone@istitutotumori.mi.it
- Tel: 0223903822
Fax: 0223902149
Access hours for medical representatives: by appointment to be agreed
Dott. Pietrantonio Filippo
Head
Dott.ssa Ambrosini Margherita
Medical Director
Dott.ssa Fazio Roberta
Medical Director
Dott. Leone Alberto Giovanni
Medical Oncologist
Dott. Manca Paolo
Medical Director
Dott.ssa Morano Federica
Medical Director
Dott.ssa Niger Monica
Medical Director
Dott.ssa Pircher Chiara Carlotta
Medical Director
Dott. Prisciandaro Michele
Medical Director
Dott.ssa Pusceddu Sara
Medical Director
Dott.ssa Raimondi Alessandra
Medical Director
Dott. Randon Giovanni
Medical Director
Oncologo Medico
- Claudia Leli
Specializzandi tesisti
- Filippo Ghelardi
- Vincenzo Nasca
- Simone Oldani
- Carolina Sciortino
Infermiere di ricerca
- Eleonora Cristarella
Study coordinator
- Maria Francesca Bosco
- Sofia Castiglione
- Anna Chiaramonte
- Salsabil Mohamed
- Federica Palermo
- Michele Palazzo
- Alessandro Salamone
Case manager
- Margherita Ghiglioni
Segreteria
- Renata Spallone
A Phase 1/2 Open-Label, Umbrella Platform Design Study to Evaluate the Safety and Efficacy of MK-2870 Plus Paclitaxel as the Second-Line Treatment of Participants With Advanced/Metastatic Gastroesophageal Adenocarcinoma:
A Phase 1/2 Study to Evaluate the Safety and Efficacy of MK-2870 Monotherapy or in Combination With Other Anticancer Agents in Gastrointestinal Cancers
A Phase 1/2 Study to Evaluate the Safety and Efficacy of Patritumab Deruxtecan in Gastrointestinal Cancers
A Phase 1b/2, multicenter, open-label study to evaluate the efficacy and safety of GSK5764227, alone or in combination with other treatments, in participants with previously treated, unresectable, or metastatic advanced
A Phase 1b/2, Open-Label Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants with Advanced or Metastatic Colorectal Cancer (61186372GIC2002 – Origami 1)
A Phase 3, Multi-Center, Randomized, Open-Label Clinical Study of Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy as First-Line Treatment in Patients With Locally Advance
A phase II, open label, multicenter trial investigating Irinotecan plus cetuximab rechallenge compared with trifluridine/tipiracil plus bevacizumab as third line treatment in circulating tumor DNA molecularly selected me
ENGIC 01 (PRODIGE 107)– COLOSOTO
A single-arm phase II study evaluating 5-fluorouracil plus Panitumumab (anti-EGFR) and Sotorasib (KRAS G12C inhibitor) in first-line treatment of patients non-eligible for a doublet/trip
Gemcitabine plus nab-PAclitaxel as switch maiNTEnance versus cONtinuation of modified FOLFIRINOX as first-line chemotherapy in patients with advanced pancreatic cancer: the PANThEON phase III Trial
Last update: 16/07/2025