On-chip tomographic microscopy: a paraDIgm Shift for RevolUtionizing lab-on-a-chiP bioimaging technology

The project is part of the prestigious European Pathfinder program for the improvement of biomedical imaging and early diagnosis of various diseases including cancer. In particular, the DISRUPT project aims to revolutionize the field of biomedical imaging by developing an integrated microscope combining photonics and wireless tomography on a chip, with microfluidics and artificial intelligence for the early diagnosis of cancer and infectious diseases. Tomography is a biomedical imaging technique commonly used in conventional CT scans capable of creating detailed images of internal organs, tissues, bones, etc. In the DISRUPT project, tomography will be used on a photonic chip in which a microfluidic system will allow the cells to slide to obtain images from refractive index maps with artificial intelligence systems. The ultimate goal is to use the technology to distinguish tumor cells from benign cells for early diagnosis and/or response to therapy.