Dr. Giandini Carlotta

Doctor

Contacts

Mail: carlotta.giandini@istitutotumori.mi.it
Tel: 0223902480

Specialty / Department

Radiotherapy

I graduated in Radiation Oncology at University of Milan with a thesis on “Volumetric Modulated Arc Therapy (VMAT) versus Intensity Modulated Proton Therapy (IMPT) for left-sided breast cancer: Dosimetric and Normal Tissue Complication Probability (NTCP) evaluation of a hypofractionated regimen (HypoRT).”

Currently, as a young radiation oncologist, I work as a professional collaborator at the Radiotherapy Department of this Foundation. I mainly focus on the treatment of breast cancer at all stages, including patients with oligometastatic and polymetastatic disease, focusing in particular on brain metastases.

I collaborate daily in a multidisciplinary setting with my colleagues in Senology and Medical Oncology. I participate as an investigator in clinical trials on breast disease, both monocentric and multicentric, observational and randomized. I co-authored clinical papers on breast cancer published in national and international journals.

ORCID Publications

• “DECIDE STUDY”: “Development and Validation of Multiparametric Radiomics Models: Characterization of the Breast Parenchyma and Prediction of the Tumor Molecular Profile” Alleanza contro il Cancro.

• “EUROPA TRIAL”: Single-modality endocrine therapy versus radiotherapy after breast-conserving surgery in women aged 70 years and older with luminal A-like early breast cancer.

• “PRISCILLA TRIAL”: Partial Radiotherapy for breast in situ carcinoma of intermediate low risk al local adjuvant treatment.

• “TAORMINA TRIAL”: Treatment of oligometastatic breast cancer-a randomized phase 3 trial comparing stereotactic ablative radiotherapy and systemic treatment with systemic treatment alone as 1st line treatment.

• “FASTPG01”: Radioterapia adiuvante ipofrazionata secondo schema ultra-ipofrazionato dopo chirurgia conservativa in pazienti affette da neoplasia della mammella.

• “RECARE”

• “RAPID SOLUTION”. Optimizing Radiotherapy Planning: An AI-Driven Solution for Breath Hold Selection in Breast Cancer. Founded by Fondazione IRCCS Istituto Nazionale dei Tumori-Valorizzazione delle Ricerca Fondi 5per1000, 2025-2026.

• “TETRIS” Risk assessment Tools for severe side Effects after breasT

Radiotherapy: radiation safety through biological extended models and dIgital twinS. HORIZON-EURATOM, 2024-2027.

• “Validating Predictive Models and Biomarkers of Radiotherapy Toxicity to Reduce Side-Effects and Improve Quality of Life in Cancer Survivors. REQUITE”. Funded by European Union’s 7th Framework Programme for research, technological development and demonstration, 2013-2018.

• “RAD-PRECISE”: Personalized radiotherapy: incorporating cellular response to irradiation in personalized treatment planning to minimize radiation toxicity”. Funded by “Joint transnational call for proposals (2018) for research projects on personalized medicine – smart combination of pre-clinical and clinical research with data and ICT solutions”, ERAPerMed, 2019-2022

• “Mechanistic computational modelling of radiation damage to microvasculature and of its effect on tumor microenvironment”. Funded by AIRC, 2019-2024.

• “ROSANNA PROJECT”: cardiotoxicity in young breast cancer patients. Funded by AIRC, 2021-2026.

• “PNNR-POC-2023-12378113” A Composite Assay for HER2-Positive Early-Stage Breast Cancer Management. Funded by PNNR 2024-2027