DISSECTING THE ROLE OF INNERVATION IN THYROID CANCER
Ente Finanziatore: Fondi 5Xmille istituzionali
Data di inizio:
Data di fine:
Struttura Principale: Biologia Integrata dei Tumori rari
PI: Mara Mazzoni - Co PI: Tiziana Di Marco
Nerves infiltrating tumors represent active components of the tumor microenvironment, playing an important role in cancer initiation and progression and providing potential targets for cancer treatment.
Some works propose the involvement of innervation in the pathogenesis of thyroid cancer, even if its role remains to be established. The aim of this study is to explore, through in vitro and in silico approaches, the contribution of innervation in thyroid cancer progression, in order to produce preliminary data providing the basis and the rationale for planning future projects.
The results will provide new knowledge about innervation as a mechanism contributing to thyroid tumor progression, helping to unveil new potential druggable targets for patients who do not respond to standard therapies.
Struttura Principale: Integrated Biology of Rare Tumors
Research Area, Departmental Simple Structure
Last update: 02/09/2025