A fully equipped laboratory (NuMeLab) is dedicated to process biological material and perform analyses in clinical biochemistry, high resolution mass spectrometry for lipidomics, HPLC/mass spectrometry for hormonal and pharmacological analyses, gas chromatography/mass spectrometry for metabolomics analyses, LC Orbitrap, ICP mass spectrometry for elemental analyses. The availability of the dedicated software LipidSearch, together with the skills of laboratory staff, allows lipidomic data processing to help identify etiological, early detection or drug response biomarkers. The NuMeLab also offers innovative applications of mass spectrometry-based breath analysis for a non-invasive early diagnosis of head/neck and breast cancers. The NuMeLab also includes a blood bank (about 175.000 samples) of the participants of lifestyle intervention randomized trials (the MeMeMe, DIANA-5, and BRCA trials).